Scientific Publications

To view all PEARRL PUBLICATIONS via the publishers website
​ (external link) please click here

To view PEARRL publications via the EU OPEN ACCESS repository
(external link) please click here
(note an embargo period may apply on full text ARTICLES)

• Henze, L. J., Griffin, B. T., Christiansen, M., Bundgaard, C., Langguth, P., & Holm, R. (2018). Exploring gastric emptying rate in minipigs: Effect of food type and pre-dosing of metoclopramide. European Journal of Pharmaceutical Sciences, 118, 183-190. doi.org/10.1016/j.ejps.2018.03.017
• Price, D. J., Ditzinger, F., Koehl, N. J., Jankovic, S., Tsakiridou, G., Nair, A., Holm, R., Kuentz, M., Dressman, J.B., Saal, C. (2018). Approaches to Increase Mechanistic Understanding and Aid in the Selection of Precipitation Inhibitors for Supersating Formulations - A PEARRL Review. Journal of Pharmacy and Pharacology. doi.org/10.1111/jphp.12927
• Effinger, A., O'Driscoll, C. M. O. D., McAllister, M., & Fotaki, N. (2018). Impact of Gastrointestinal Disease States on Oral Drug Absorption – implications for formulation design – a PEARRL review. Journal of Pharmacy and Pharmacology. DOI: 10.1111/jphp.12928
• O'Dwyer, P.J., Litou, C., Box, K. J., Dressman, J. B., Kostewicz, E. S., Kuentz, M., Reppas, C. (2018). In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review. Journal of Pharmacy and Pharmacology. doi.org/10.1111/jphp.12951
• O'Shea, J. P., Holm, R., O'Driscoll, C. M., Griffin, B. T. (2018). Food for thought: formulating away the food effect - a PEARRL Review. Journal of Pharmacy and Pharmacology. doi.org/10.1111/jphp.12957
• Guimarães, M., Statelova, M., Holm, R., Reppas, C., Symilllides, M., Vertzoni, M., Fotaki, N. (2018).  Biopharmaceutical considerations in paediatrics with a view to the evaluation of orally administered drug products – a PEARRL review. Journal of Pharmacy and Pharmacology. doi.org/10.1111/jphp.12955
• Jankovic, S., Tsakiridou, G., Ditzinger, F., Koehl, N.J., Price, D.J., Ilie, a.R., Kalantzi, L., Kimpe, K., Holm, R., Nair, A., Griffin, B., Saal, C., Kuentz, M. (2018). Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - A PEARRL Review. Journal of Pharmacy and Pharmacology. doi.org/10.1111/jphp.12948
• Henze, L.J., Koehl, N.J., O'Shea, J.P., Kostewicz, E.S., Holm, R., Griffin, B.T. (2018). The pig as a pre-clinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosage forms: a PEARRL review. Journal of Pharmacy and Pharmacology. doi.org/10.1111/jphp.12912
• Ditzinger, F., Price, D.J., Ilie, A.R., Köhl, N.J., Jankovic, S., Tsakiridou, G., Aleandri, S., Kalantzi, L., Holm, R., Nair, A., Saal, C., Brendan Griffin, B., Kuentz, M. (2018). Lipophilicity and hydrophobicity considerations in bio-enabling oral formulations approaches – a PEARRL review. Journal of Pharmacy and Pharmacology. doi: 10.1111/jphp.12984
• Chara Litou C., Effinger A., Kostewicz E.S., Box K.J., Fotaki N., Dressman J.B. (2018). Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: a PEARRL Review. Journal of Pharmacy and Pharmacology. https://doi.org/10.1111/jphp.12983
• Aleandri S., Jankovic S., Kuentz M. (2018). Towards a better understanding of solid dispersions in aqueous environment by a fluorescence quenching approach. International Journal of Pharmaceutics. 2018 Aug 18;550(1-2):130-139. https://doi.org/10.1016/j.ijpharm.2018.08.029 doi.org/10.1016/j.ijpharm.2018.08.029
• Pentafragka C., Symillides M., McAllister M., Dressman J.B., Vertzoni M., Reppas C. (2018) The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and in silico simulations: a PEARRL review. Journal of Pharmacy and Pharmacology. https://doi.org/10.1111/jphp.12999