Dr. Andrea Edginton
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Background |
Dr. Andrea Edginton is an Associate Professor at the School of Pharmacy at the University of Waterloo in Ontario, Canada and co-owner of the PBPK consulting company, Design2Code Inc. Before coming to the University, she helped to develop PK-Sim in the Systems Biology group at Bayer Technology Services in Leverkusen, Germany. Dr. Edginton’s academic research focuses on the development and application of physiologically-based pharmacokinetic (PBPK) models and simulation techniques in both the areas of pharmaceuticals and human health risk assessment. Her research examines how the physiology of sub-populations such as children and patients with disease affect the pharmacokinetics of drugs and how this information can be integrated into PBPK models for the optimization of drug therapy. Dr. Edginton also heads the technical component of the Web-Accessible Population Pharmacokinetics Service – Hemophilia (WAPPS-Hemo.ca) project that uses population pharmacokinetic model and Bayesian forecasting for tailoring treatment prophylaxis in persons with hemophilia. The service is used by over 120 clinical sites around the globe for over 1700 patients (and counting) and contains the largest PK dataset of factor concentrates.
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Key Publications
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