Dr. L. Kalantzi
Pharmathen SA, Product Design & Evaluation, Greece

Position
Currently she holds the role of Scientific Affairs manager in Pharmathen SA, a pharmaceutical company mainly focused in the development of complex generic and supergeneric drug products.

Background
Dr . Lida Kalantzi has a Pharmacy degree from the University of Athens where she has also acquired an MSc in Industrial Pharmacy and a PhD in Biopharmaceutics. She has then moved to work in Health Care Authorities (Clinical Assessor at Greek National Organization for Medicines, Delegate at Paediatric Committee/EMA, and member of PK drafting Group/EMA) and later on in Pharmaceutical Industry (GSK (UK), Pharmathen (Greece). Her expertise includes the in vitro and in vivo assessment of new dosage forms as well as the design and the assessment of clinical studies including those targeting special populations (i.e. children).

Role in PEARRL
Main Supervisor ESR 4, Co-Supervisor ESR 5 and ESR 7

Key Publications
  • Kechagia IA, Kalantzi L Dokoumetzidis A . Extrapolation of valacyclovir posology to children based on pharmacokinetic modelling . J Pediatr Infect Dis. 2015; 34:1342-1348.
  • Kechagia IA, Kalantzi L, Dokoumetzidis A. (2015) Extrapolation of enalapril efficacy from adults to children using pharmacokinetic/pharmacodynamic modelling J Pharm Pharmacol. Nov;67(11):1537-45.
  • Kalantzi LE, Karavas E, Koutris EX, Bikiaris DN. Recent advances in oral pulsatile drug delivery, Recent Pat Drug Deliv Formul 3(1):49-63 (2009)
  • Kalantzi L, Page R, Nicolaides E, Digenis G, Reppas C. In vitro methods can forecast the effects of intragastric residence on dosage form performance. Eur J Pharm Sci 23;33(4-5):445-51 (2008)
  • Kalantzi L, Persson E, Polentarutti B, Abrahamsson B, Goumas K, Dressman JB, and Reppas C. Canine Intestinal contents vs Simulated media for the assessment of solubility of two weak bases in the human small intestinal contents. Pharm Res.  Jun;23(6):1373-1381 (2006).
  • Kalantzi L, Goumas K, Kalioras V, Abrahamsson B, Dressman JB, Reppas C. Characterization of the human upper gastrointestinal contents under conditions simulating bioavailability/bioequivalence studies. Pharm Res.  Jan;23(1):165-76 (2006).