PEARRL Online Learning Portal (Members only)

Over the course of the PEARRL project specialised post-graduate (PG) training modules will be provided via the PEARRL Online Learning Portal (available to members only). Each PG module will be delivered using a blended learning approach (i.e. a combination of online and face-to-face teaching at the annual meeting).

Available Training Modules

Various speakers from in and outside of the PEARRL consortium have held lectures on multiple topics relevant to the PEARRL project. The sessions have been recorded and made available to PEARRL members on the PEARRL Online Learning Portal. 

Science and Technology training

• "Pimp my Drug" - The need for Bioenabling formulations
  Prof. Jennifer Dressman
• “Life is a matter of fat” – Lipid formulations
  Dr. Brendan Griffin
• "Nuts and bolts of amorphous drug systems" - get a first overview of solid dispersions"
  Prof. Martin Kuentz
• "Adsorption for Absorption?" - Mesoporous silica formulations
  Dr. Abina Crean
• "Ring-A-Ling" - Cyclodextrins and the art of inclusion
  Dr. Rene Holm, Janssen, Belgium)
• "Nanosize me!"-  Smaller may be better for drug absorption
  Jan Möschwitzer (Invited speaker)
• "The Urge to Merge" - hot melt extrusion
  Dr. Justin Yiwei Tian (Queens University Belfast)
• "To salt or not to salt?" Free base or salt form?
  Dr. Christoph Saal

   Industrial pharma training

• An overview of the drug discovery process
  Dr. Christoph Saal
• An overview of the development process in innovative companies
  Dr. Mark McAllister
• An overview of the development process of generic drug products
  Dr. Lida Kalantzi
• Focus on the CMC part
  Dr. Rene Holm

  Regulatory science training: Tools and Approaches for Assessing Medicines

• Nuts and bolts of PBPK Modeling for oral drug absorption
  Dr. Rodrigo Cristofoletti
• How PBPK is set up to describe DDI
  Dr. Oliver Hatley
• Pediatric PBPK: growth and maturation, model development workflow and regulatory aspects
  Dr. Andrea Edginton
• Applications of PBPK at the FDA
  Dr. Mehul Mehta
• Understanding food effects
  Prof. Jennifer Dressman
• Understanding precipitation of weak bases in the GIT
  Dr. David Turner
• Prediction of clinically based BE: case example ibuprofen, ibuprofen salts
  Dr. Rodrigo Cristofoletti
• Extrapolating the healthy adult dose-exposure relationship to special populations using PBPK
  Dr. Andrea Edginton
• Biopharmaceutics and Clinical Relevance: The FDA point of view
  Dr. Mehul Mehta
• Industrial perspectives on the use of predictive biopharmaceutics tools
  Dr. Mark McAllister
• Small scale models: Usefulness, challenges and their potential for implementation by regulatory authorities
  Dr. Karl Box
• The transfer model for evaluation the of supersaturation and precipitation in the small intestine after oral drug product administration: Usefulness, challenges and its potential for implementation by regulatory authorities
  Dr Edmund Kostewicz
• The BioGIT model for evaluating the impact of gastrointestinal transfer on luminal concentrations in the fasted state: Usefulness, challenges and its potential for implementation by regulatory authorities
  Dr. Maria Vertzoni
• Experiences with the simulation of gastric (hydro)dynamics with a view in the development of a useful in vitro tool
  Prof. Werner Weitschies
• The Dynamic Gastric System in the evaluation of oral drug products: Usefulness and Challenges
  Prof. Anette Müllertz
• The use of TIM-1 system for the evaluation of oral drug products in a regulatory setting
  Dr. Richard Barker

Transferable and career skills workshops

• Scientific presentation skills - introduction
  Prof. Alan Kelly
• Preparing scientific presentations and posters
  Prof. Alan Kelly
• Public speaking and stage presence: Theatre-based training to present with impact (GRADE)
  Ms. Lena Wolf

Upcoming Training Modules

• Molecule to Medicine: How Formulation Science Delivers
  
• Career management skills for the Pharmaceutical R&D sector