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ESR 13: Ioannis Loisios-Konstantinidis
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PEARRL research
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Ioannis will apply biorelavant dissolution testing to BCS class II compounds with a view of replacing in vivo pharmacokinetic studies with in vitro tests to determine bioequivalence in the fasted and fed state. The results will be utilized to fully characterize formulations containing BCS class II drugs and will be coupled with in silico models in order to create new in vitro methods for predicting in vivo performance and also establish a "safe space" between bio- and therapeutic- equivalence of bio-enabling formulations containing BCS class II compounds with the aim of validating the proposed methods.
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Host
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Johann Wolfgang Goethe University, Institute of Pharmaceutical Technology
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Supervisory Team
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Scientific Background
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Ioannis received his Diploma of Pharmacy from the School of Pharmacy, National and Kapodistrian University of Athens, Greece (2011-2016). During his Erasmus+ semester at the Department of Pharmacokinetics and Toxicokinetics, Aix-Marseille University, France, Ioannis completed his diploma thesis, which was entitled: "Pharmacokinetic Modeling & Simulation of Time-Lags observed in the Enterohepatic Recirculation using Differential Difference Equations: Numerical and Analytical Approaches."
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Contact
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Loisios-Konstantinidis [at] em [dot] uni-frankfurt [dot] de
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